Manohary Rajendram

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Antibiotics targeting DNA gyrase have been a clinical success story for the past half-century, and the emergence of bacterial resistance has fueled the search for new gyrase inhibitors. In this paper we demonstrate that a new class of gyrase inhibitors, the gyramides, are bacteriostatic agents that competitively inhibit the ATPase activity of Escherichia(More)
Studied protein-lipid interactions occurring and identified a novel regulator of anionic phospholipid biosynthesis in Escherichia coli. Performed biophysical characterization of protein-membrane binding interfaces using fluorimetry. Identified proteins necessary for various metabolic processes in Homo sapiens sapiens by building interactome maps for(More)
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