Mano J Thubrikar

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BACKGROUND The downward movement of the aortic root during the cardiac cycle may be responsible for producing the circumferential tear observed in aortic dissections. METHODS AND RESULTS Contrast injections were investigated in 40 cardiac patients, and a finite element model of the aortic root, arch, and branches of the arch was built to assess the(More)
Aortic valve leaflets undergo extraordinary flexion due to the complete reversal of their curvature during billions of cardiac cycles. The flexion stresses in the leaflet depend on its elastic modulus which we investigated in vivo and in vitro. In six dogs, we placed radiopaque markers on an aortic leaflet. Leaflet length was calculated from the marker(More)
OBJECTIVE Valve-sparing surgery can be used in patients with dilated aortic roots and aortic insufficiency (AI) but has not become a common practice, in part because the spared valve may be incompetent. Our goal was to study how the dimensions of the aortic root and leaflets have changed in such patients. METHODS Fourteen patients with dilated aortic root(More)
INTRODUCTION The cause of ascending aortic dilatation occurring in patients with congenitally bicuspid aortic valves was investigated. METHODS Flow patterns through human aortic roots with congenitally bicuspid aortic valves as well as through porcine constricted aortas were studied in a left heart simulator. Vibration was recorded as a measure of(More)
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