Manny Saltiel

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Twenty-nine patients were treated for carcinoma of the head and neck with a combination of cisplatin, vincristine, and bleomycin. Four of these patients had acute vascular episodes (three had cerebrovascular accidents and one developed Raynaud's phenomenon) during or after treatment. Two additional patients with a similar history and course are also(More)
Kidney transplant patients receiving phenytoin or phenobarbital may have decreased graft survival. These drugs have been shown to enhance the metabolism of glucocorticoids. We determined the disposition of total and unbound prednisolone in six stable kidney transplant patients receiving prednisone for immunosuppression and phenytoin or phenobarbital for a(More)
The low molecular weigh heparins (LMWHs) are primarily eliminated renally, and current literature indicates that there is a reduction in clearance and an increase in half-life of LMWHs in patients with severe chronic kidney disease (CKD) associated with elevated anti-Xa levels and an increased risk of bleeding. It therefore becomes clinically prudent to(More)
It is with great pleasure that we bring you this issue of Journal of Pharmacy Practice, the first of two consecutive issues that focus on anticoagulation. With the assumption that readers of the Journal are familiar with the basic pharmacology of commonly used anticoagulants, we have chosen to focus on several challenging and/or controversial areas. This(More)
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