Manmohan M. Laloraya

Learn More
The autoimmune regulator (AIRE) protein is a putative transcription regulator with two plant homeodomain-type zinc fingers, a putative DNA-binding domain (SAND), and four nuclear receptor binding LXXLL motifs. We have shown here that in vitro, recombinant AIRE can form homodimers and homotetramers that were also detected in thymic protein extracts.(More)
From the 1st to 6th days of pregnancy in the rat, while the blastocyst is still in the fallopian tube, there is high peroxidase activity in the corpus luteum, the blastocyst, and there is high peroxidase activity in the endometrium. On day 8 of pregnancy, peroxidase activity in the corpus luteum begins to fall rapidly, and there is a sharp rise in the(More)
The aim of this study was to investigate the presence of iNOS in the murine uterus and embryo at implantation. Western blot analysis showed the presence of a 130-kDa band with strong reactivity to anti-iNOS antibody in the pre- and peri-implantation stage uteri. This band was faint in the postimplantation uteri. Immunocytochemical studies showed a heavy(More)
The lutropin-induced depletion of ascorbate in corpora lutea of albino-rat ovary is shown to be associated with the induction of peroxidase in corpora lutea. An inverse relationship between ascorbate depletion and peroxidase activity was established in a time-course study with lutropin. Analyses made at different phases of the reproductive cycle are in(More)
Even though the aminopeptidase and amylase are the major liquefying factors in the liquefaction process of the ejaculated semen-coagulum, the exact nature of "switching on" phenomena has not been elucidated yet. Monitoring the rate of production of the asborbyl radical, an indirect method for oxyradical-stress measurement, this prima facie study reports the(More)
Steigfli issigkeit h a t sich ein Gemisch von i -Propanol , \ u u n d Eisessig (20:5:2) u n d als Papie r Schleicher u n d Schflll Nr. 2043b bew~hr t . Die zu u n t e r s u c h e n d e L 6 s n n g wird mi t Ace ta t oder Ci t ra tpuf fe r an! PH 3 gebrach t . Wil l m a n die dabei e n t s t e h e n d e Ve rd f i nnung vermeiden , so k a n n auch mi t ether(More)
Papierchromatographische Analysen der freien Aminosäuren und Amide in gesunden und mit «yellow mosaic»-Virus infizierten Blättern vonAbelmoschus esculentus zeigen neben einer Zunahme von Leucin, Phenylalanin, Valin + Methionin und Asparaginsäure die Bildung einer neuen, ninhydrinpositiven Substanz und Asparagin in den infizierten Blättern. Es werden(More)
  • M Laloraya
  • Biochemical and biophysical research…
  • 1990
The endometrial phospholipid bilayer is shown to be in a highly fluid and polar state at the time of implantation in Mus musculus as evidenced from a spin label study using the stearic acid spin label, 5-doxyl stearate. The positive correlation observed between the superoxide anion radical levels and the fluidity and polarity state of the endometrial cells(More)
In this study, we examined the effect of 17 beta-estradiol and selected antiestrogens on uterine NADPH-oxidase activity, superoxide dismutase (SOD) activity, hydride (H.-), dienyl radical and O2 -radical generation, and membrane fluidity. NADPH oxidase activity was positively modulated in estradiol-treated animals and negatively regulated in animals that(More)
The distribution of various simple sugar residues over the spermatozoa surfaces of five different mammalian species is characterized and compared. Epididymal maturation of the spermatozoa of all the five species studied exhibited an increase in the amount of N-acetyl-D-glucosamine residues over their acrosomal domains. A complete blockade of sperm-zona(More)