Manjunath Kulkarni

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BACKGROUND Optimum timing of the initiation of dialysis therapy in acute kidney injury is not clear. STUDY DESIGN Prospective, open label, 2-arm, randomized, controlled trial. SETTING & PARTICIPANTS 208 adults with acute kidney injury with progressively worsening azotemia at the artificial kidney dialysis unit of a tertiary-care referral center in(More)
OBJECTIVE To study the clinico-epidemiological profile of children hospitalized with dengue illness. METHODS Prospective study of children hospitalized with the diagnosis of dengue illness during from September through November 2006 at a tertiary care centre in Jaipur. RESULTS A total of 948 children including 671 (70.8%) boys and 277 (29.2%) girls were(More)
BACKGROUND Epidemiology of minimal-change disease (MCD) in adults differs from that in children and is not studied well in Indian population. METHODS We retrospectively studied the records of 61 adult patients with MCD to assess clinical, laboratory and histopathological features, and to evaluate the response to treatment, course and complications of the(More)
A nine year old boy, born of third degree consanguinity, presented with a hard left scapular swelling for 6 months. There was no history of fever, trauma or weight loss. There was no pain, redness or discharge. This mass was excised but recurred over the next 6 months (Left panel of Figure 1). A similar swelling had been excised from the left knee one year(More)
We report a case of a 66-year-old diabetic patient who presented with muscle weakness 2 weeks after kidney transplantation. Her immunosuppressive regimen included tacrolimus, mycophenolate mofetil, and steroids. She was found to have hyperkalemia and normal anion gap metabolic acidosis. Tacrolimus levels were in therapeutic range. All other drugs such as(More)
We report a case of a young female patient who presented with weakness of upper and lower limbs. On evaluation, she had hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria. Anti-Ro (SSA) antibody was positive. She had an acquired Gitelman syndrome due to primary Sjögren's syndrome (SS). SS presenting with features of Gitelman syndrome is very(More)
Infections are Achilles heel of kidney transplant recipients. Opportunistic fungal infections are increasingly recognized in these patients. We report a case of kidney transplant recipient with skin and soft tissue infection caused by Pyrenochaeta romeroi, a dematiaceous fungi. Infection by this organism is rare.
Introduction Hyponatremia is the most common electrolyte abnormality seen in clinical practice. It occurs in wide variety of clinical conditions. Studies have shown that presence of hyponatremia is a risk factor for morbidity and mortality. Despite hyponatremia being a commonly encountered condition, there is no consensus in its management. Recently(More)