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Automatic construction of knowledge graphs (KGs) from unstructured text has received considerable attention in recent research, resulting in the construction of several KGs with millions of entities (nodes) and facts (edges) among them. Unfortunately, such KGs tend to be severely sparse in terms of number of facts known for a given entity , i.e., have low(More)
During infection in the gastrointestinal tract, enterohemorrhagic Escherichia coli (EHEC) O157:H7 is exposed to a wide range of signaling molecules, including the eukaryotic hormones epinephrine and norepinephrine, and bacterial signal molecules such as indole. Since these signaling molecules have been shown to be involved in the regulation of phenotypes(More)
To utilize biofilms for chemical transformations in biorefineries they need to be controlled and replaced. Previously, we engineered the global regulator Hha and cyclic diguanylate-binding BdcA to create proteins that enable biofilm dispersal. Here we report a biofilm circuit that utilizes these two dispersal proteins along with a population-driven(More)
Although the process of drug development requires efficacy and toxicity testing in animals prior to human testing, animal models have limited ability to accurately predict human responses to xenobiotics and other insults. Societal pressures are also focusing on reduction of and, ultimately, replacement of animal testing. However, a variety of in vitro(More)
Pseudomonas aeruginosa is becoming recognized as an important pathogen in the gastrointestinal (GI) tract. Here we demonstrate that adenosine, derived from hydrolysis of ATP from the eucaryotic host, is a potent interkingdom signal in the GI tract for this pathogen. The addition of adenosine nearly abolished P. aeruginosa biofilm formation and abolished(More)
In a distributed environment, one of the major concerns is authentication of remote users. In this sector, legitimate users are more powerful attackers. The remote systems working with password and smart card ensures authorised access. Smart card based remote user authentication schemes have been adopted due to their low computation cost and portability. In(More)
Visualizing 2-D/3-D embeddings of image features can help gain an intuitive understanding of the image category landscape. However, popular visualization methods of visualizing such embeddings (e.g. color-coding by category) are impractical when the number of categories is large. To address this and other shortcomings, we propose novel quantitative measures(More)
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