Manju Bhaskar

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Context aware E-Learning systems provide learning content according to a learner’s context. In the existing context aware E-Learning systems there is no standardized set of context parameters considered and content is adapted based on a randomly considered set of parameters. In this work, a standardization of context model for context aware E-learning has(More)
Context aware e-learning system helps to provide elearning contents which are customized according to the learner’s context. For generating context aware contents many adaptation parameters have to be considered. Customized learning path is one such adaptation parameter. In the existing elearning systems, learning paths is generated using several(More)
Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor dysfunction. Recent evidence indicates that cyclin-dependent kinase 5 (Cdk5) is inappropriately activated in several neurodegenerative conditions,(More)
In a series of studies, we have identified TFP5, a truncated fragment of p35, the Cdk5 kinase regulatory protein, which inhibits Cdk5/p35 and the hyperactive Cdk5/p25 activities in test tube experiments. In cortical neurons, however, and in vivo in Alzheimer's disease (AD) model mice, the peptide specifically inhibits the Cdk5/p25 complex and not the(More)
Cyclin-dependent kinase 5 (CDK5) is a multifunctional serine/threonine kinase that regulates a large number of neuronal processes essential for nervous system development and function with its activator p35 CDK5R1. Upon neuronal insults, p35 is proteolyzed and cleaved to p25 producing deregulation and hyperactivation of CDK5 (CDK5/p25), implicated in tau(More)
Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles, it is well documented that cyclin-dependent kinase 5 (CDK5), a critical neuronal protein kinase in nervous system development, function, and survival, when deregulated and hyperactivated induces Alzheimer's disease (AD) and amyotrophic lateral sclerosis and Parkinson's(More)
Bandstop filters are realized by etching periodic patterns of complementary split ring resonators(CSRR) on the ground plane, exactly below the central microstrip transmission line. This article presents hexagonal CSRR in the design of a band bandstop filter with stopbands at 1.45GHz. First, a regular hexagonal shaped CSRR is used to realize a bandstop(More)
Adaptive E-learning refers to adapt the way of presentation of educational material according to the student's needs. Understanding ability differs by student to student so the learning path should vary according to their understanding ability. Some students may understand by once some may needs more with different way. This paper represents a same(More)
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