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Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a beta-keto ester or beta-diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or -thiones in excellent yields.
A series of benzofuran-based chalconoids 6a-v were designed and synthesized as new potential AChE inhibitors. The in vitro assay of synthesized compounds 6a-v showed that most compounds had significant anti-AChE activity at micromolar or sub-micromolar levels. Among the tested compounds, 3-pyridinium derivative 6m bearing N-(2-bromobenzyl) moiety and… (More)
In this paper, an electrokinetic flow of a water electrolyte in a nano-channel will be studied. This study will be with existence of the Electric Double Layer (EDL) and fully analytical. Governing equation for the EDL is Poisson-Boltzmann. In addition, Navier-Stokes equations for electrolyte flow, Species and mass conservation equations are in use. Induced… (More)