Manish Patel

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INTRODUCTION Chromosomal rearrangements involving neurotrophic tyrosine kinase 1 (NTRK1) occur in a subset of non-small cell lung cancers (NSCLCs) and other solid tumor malignancies, leading to expression of an oncogenic TrkA fusion protein. Entrectinib (RXDX-101) is an orally available tyrosine kinase inhibitor, including TrkA. We sought to determine the(More)
In 2006 Google designed and implemented a TV Show search system which featured a dual-navigation control combining a powerful search system with an interactive, personalize-able TV listings grid. The dual-control system allowed users to move fluidly between explicit search and general discovery, obtain detailed information without leaving the global context(More)
MELANOMA BRIDGE 2015 KEYNOTE SPEAKER PRESENTATIONS Molecular and immuno-advances K1 Immunologic and metabolic consequences of PI3K/AKT/mTOR activation in melanoma Vashisht G. Y. Nanda, Weiyi Peng, Patrick Hwu, Michael A. Davies K2 Non-mutational adaptive changes in melanoma cells exposed to BRAF and MEK inhibitors help the establishment of drug resistance(More)
Total harmonic distortion (THD) is a term used to describe the net deviation of a nonlinear waveform from ideal sine waveform characteristics. Total harmonic distortion is the ratio between the RMS value of the harmonics and the RMS value of the fundamental. In multilevel Inverter As we try to increase the number of levels THD reduces. This paper contains(More)
Cell competition is identified as a crucial phenomenon for cancer and organ development. There is a possibility that microRNAs (miRNAs) may play an important role in the regulation of expression of genes involved in cell competition. In silico screening of miRNAs is an effort to abridge, economize and expedite the experimental approaches to identification(More)
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