Manish G Gangrade

  • Citations Per Year
Learn More
Amphotericin B is available in various drug delivery systems such as cholesteryl sulfate complex, as lipid complex, and as liposomal formulation. The separation and measurement of free drug (drug which is not bound with liposomal lipids) and liposomal drug (drug which is entrapped in liposomes) in the human plasma after injection of liposomal Amphotericin B(More)
A sensitive and specific high-performance liquid chromatography (HPLC) method for the separation and quantification of 3-(S)-quinuclidinol in 3-(R)-quinuclidinol, precursor for active pharmaceutical ingredients (solifenacin, revatropate and talsaclidine), has been developed and validated by precolumn derivatization. Several chiral columns were tested in a(More)
Enantiomer specific method development is essential to ensure the safety and efficacy of the drug. Topotecan is the first topoisomerase inhibitor developed for ovarian cancer and lung cancer. Simple, rapid enantio specific chromatographic method was developed for R (-) enantiomer control in topotecan with immobilized chiral stationary phase (CSP). Chiral(More)
  • 1