Mangala Devi Manandhar

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From the leaves of Sarcococca coriacea two new steroidal alkaloids, epoxynepapakistamine-A [(20S)-20-(N-methylamino)-3beta-(tigloylamino)-5alpha-pregna-16alpha,17alpha-epoxy-2beta,4beta-di-O-acetate] (1), and epoxysarcovagenine-D [(20S)-20-(N-methylamino)-3beta-(tigloylamino)-5alpha-pregna-2-en-16alpha,17alpha-epoxy-4-one] (2), and two known compounds(More)
The crude extracts of tubers of Aconitum spicatum (Bruhl) Stapf were investigated for in vitro antileishmanial activity against Leishmania major. The dichloromethane extract at pH 2.5 showed antileishmanial activity with IC50 value of 27.10 ± 0.0 μg/mL. Chromatographic purification of the dichloromethane extract led to isolation of three C-19 norditerpenoid(More)
Phytochemical and biological screening of root of Asparagus racemosus was studied. The brine shrimp bioassay of its various extracts showed that the methanol (MeOH) extract was biologically active. The column chromatography of hexane, acetone and methanol extracts resulted in the isolation of 9hexadecanoic acid-9-octadecenylester (Z,Z), β-Sitosterol,(More)
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