Manfred K. Grieshaber

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Hydrogen sulfide is a potent toxin of aerobic respiration, but also has physiological functions as a signalling molecule and as a substrate for ATP production. A mitochondrial pathway catalyzing sulfide oxidation to thiosulfate in three consecutive reactions has been identified in rat liver as well as in the body-wall tissue of the lugworm, Arenicola(More)
Many aquatic animal species can survive sulfide exposure to some extent through oxidation of the sulfide, which results mainly in thiosulfate. In several species, sulfide oxidation is localized in the mitochondria and is accompanied by ATP synthesis. In addition, blood-based and intracellular compounds can augment sulfide oxidation. The formation of(More)
The acid-base status of extra- and intracellular fluids was studied in relation to the anaerobic energy metabolism in the adductor muscle, mantle, gills, and heart of the marine bivalve Crassostrea gigas after exposure to air for periods of 2, 4, 8, 12, 24, and 48 h. Such exposure was found to cause a significant reduction in the pH in the hemolymph (pH(e))(More)
Oxygen consumption, anaerobic metabolism, and oxygen supply of inner tissues were analysed in Sipunculus nudus at different oxygen tensions. Oxygen consumption, energy expenditure, and the PO2 in the coelomic fluid decreased linearly with declining ambient PO2. Below a certain range of PO2, which was a function of the size of the animals, the rate of oxygen(More)
Mitochondria occur as aerobic, facultatively anaerobic, and, in the case of hydrogenosomes, strictly anaerobic forms. This physiological diversity of mitochondrial oxygen requirement is paralleled by that of free-living alpha-proteobacteria, the group of eubacteria from which mitochondria arose, many of which are facultative anaerobes. Although ATP(More)
Oxygen uptake and the mode of energy production in Sipunculus nudus L. were determined at different oxygen levels by means of direct and indirect calorimetry. Oxygen consumption declined linearly with decreasing ambient POr A similar decrease in heat production was observed down to a Po2 of 8.66 kPa. At lower oxygen tensions, a discrepancy between aerobic(More)
Since its invasion of Europe in the early 1980s, the Asian clam Corbicula fluminea has become very abundant in nearly all western river systems. Today this species is one of the most important biomass producers in the River Rhine. Monitoring the valve movements of C. fluminea over a period of 2 years revealed a circadian rhythm in summer, with extended(More)
1. The scallopChlamys opercularis uses jet propulsion swimming as a means of escape if attacked by the star fishMarthasterias glacialis. The energy for these rapid movements is supplied by the depletion of the phosphagen phospho-L-arginine. During escape swimming the energy charge of the adductor muscle drops from 0.93 to 0.42. Due to the decrease of(More)
The modulation of haemocyanin oxygen affinity was studied at 10 degrees C in the blood of the intertidal prawn Palaemon elegans. On increasing the L-lactate concentration in dialysed blood from 0 to 9.1 mM, P50 decreased from 27 to 11 torr at pH 7.8. Undialysed blood exhibited a higher oxygen affinity than dialysed blood with the same lactate concentration(More)