Manfred D. Laubichler

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SYNOPSIS. Developmental Evolution (DE) contributes to various research programs in biology, such as the assessment of homology and the determination of the genetic architecture underlying species differences. The most distinctive contribution offered by DE to evolutionary biology, however, is the elucidation of the role of developmental mechanisms in the(More)
The difference in phenotypes of queens and workers is a hallmark of the highly eusocial insects. The caste dimorphism is often described as a switch-controlled polyphenism, in which environmental conditions decide an individual's caste. Using theoretical modeling and empirical data from honeybees, we show that there is no discrete larval developmental(More)
Theodor Boveri's major intellectual contribution was his focus on the causality of nuclear chromosomal determinants for embryological development. His initial experimental attempt to demonstrate that the character of the developing embryo is determined by nuclear rather than cytoplasmic factors was launched in 1889. The experimental design was to fertilize(More)
The evolution and development of complex phenotypes in social insect colonies, such as queen-worker dimorphism or division of labor, can, in our opinion, only be fully understood within an expanded mechanistic framework of Developmental Evolution. Conversely, social insects offer a fertile research area in which fundamental questions of Developmental(More)
I n a recent and well-publicized case, two northern snakeheads (Channa argus)— an Asian fish often raised for food in flooded rice paddies—were discovered along with a cohort of fingerling progeny in a suburban Maryland pond. State biologists all but panicked, and the media converged on the pond for a photo opportunity to go with the news story. Metaphors(More)
Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics. Conflicting conceptions of function continue to be used in the scientific literature to(More)