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Environmental factors are implicated in aging as well as genetic predisposition-induced Parkinson’s disease (PD) pathogenesis. Wrongdoers increase oxidative stress and nitrosative burden, which eventually degenerate the nigrostriatal dopaminergic neurons. Inhibition of the expression of nitric oxide synthase (NOS), an enzyme responsible for nitric oxide(More)
Detection of malignancy from histopathological images of breast cancer is a labor-intensive and error-prone process. To streamline this process, we present an efficient Computer Aided Diagnostic system that can differentiate between cancerous and non-cancerous H&E (hemotoxylin&eosin) biopsy samples. Our system uses novel textural, topological and(More)
Two novel methods are proposed for robust segmentation of pulmonary nodules in CT images. The proposed solutions locate and segment a nodule in a semi-automatic fashion with a marker indicating the target. The solutions are motivated for handling the difficulty to segment juxtapleural, or wall-attached, nodules by using only local information without a(More)
To identify Binteresting[ images, human observers view 10 images/sec, while electroencephalography (EEG) signals from the observers own brains are automatically decoded. ABSTRACT | Our society's information technology advancements have resulted in the increasingly problematic issue of information overloadVi.e., we have more access to information than we can(More)
This study was planned to observe the clinical and radiological course of single small enhancing CT lesions in Indian patients presenting with new-onset-seizures. In this study, 75 patients with new-onset seizures and a single enhancing CT lesion were prospectively followed up for 1 year. All patients fulfilled the criteria of cysticercus granuloma. The(More)
Subacute sclerosing panencephalitis (SSPE) is a slowly progressive inflammatory disease of the central nervous system caused by a persistent measles virus usually affecting the childhood and adolescent age group. Clinical features at onset are very subtle and non-specific. Certain atypical features can occur at onset or during the course of illness which(More)
INTRODUCTION Diffusion tensor tractography (DTT) is a newer magnetic resonance imaging (MRI) technique that helps in evaluation of white matter. Presurgical planning with tractography may be valuable for evaluation of white matter tracts and their relationship with epileptogenic focus and for evaluation of cortical fibres around the epileptogenic zone. (More)
We consider the problem of segmentation of images that can be modelled as piecewise continuous signals having unknown , non-stationary statistics. We propose a solution to this problem which first uses a regression framework to estimate the image PDF, and then mean-shift to find the modes of this PDF. The segmentation follows from mode identification(More)
OBJECTIVE Spirometry is the most common test recommended to monitor respiratory dysfunction in patients of amyotrophic lateral sclerosis (ALS). However, the test depends on the patient's efforts and may be difficult to conduct in patients with faciobulbar weakness. We aimed to study the role of phrenic nerve-electrophysiological studies to predict(More)