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PURPOSE The aim of this study was to evaluate pamidronate for bone pain in a randomised double-blind trial and to evaluate the contribution of new markers of bone resorption in patients with bone metastases. PATIENTS AND METHODS Fifty-two patients with painful bone metastases were randomised to receive a two-hour infusion of pamidronate 120 mg or an(More)
OBJECTIVE Oestrogen replacement therapy is associated with a marked reduction in coronary event rates in post-menopausal women. As older age is associated with progressive arterial endothelial damage, a key event in atherosclerosis, we assessed whether hormone replacement therapy (HRT) with oestrogen alone, or oestrogen and progesterone combined, is(More)
  • Mandy Abbey
  • Nursing standard (Royal College of Nursing (Great…
  • 1997
It is estimated that by the 21 st century over 60 per cent of cancer patients will survive beyond the five-year range ( Tuls-Halstead and Fernsler 1994 , La Fortune- Fredette 1995 ). Evidence from cancer registry data shows that even in 1987 the percentage of people surviving cancer beyond five years was greater than 50. Figures 1 and 2 show survival rates(More)
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