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Empirical data about contact frequencies of children is needed for estimating parameters in mathematical modelling studies that investigate the effect of targeting influenza intervention to children. A survey about the social contacts of school children was conducted in a primary school in Germany. The distribution of the daily numbers of contacts was(More)
BACKGROUND Child abuse is a recognized public health and social problem worldwide. Using data from the Multiple Indicator Cluster Surveys (MICS) we aimed to (i) compare different forms of child abuse across countries and regions, and (ii) examine factors associated with different forms of child abuse. METHODS Information on child abuse was available in 28(More)
OBJECTIVE We examined the feasibility of combining communication by e-mail and self-collection of nasal swabs for the prospective detection of acute respiratory infections in a non-medical setting. METHODS The study was conducted among a convenience sample of employees (n=53) at a research institution (December 2009-April 2010). Real-time data on the(More)
BACKGROUND Increased migration volume and different Hepatitis B prevalence between immigration and emigration countries have changed the Hepatitis B virus (HBV) epidemiology considerably in Northern and North-Western European migrants-receiving countries. Due to the difference in migration status monitoring, the HBV infection data on migrants are not easily(More)
BACKGROUND This study assessed the extent of delays in childhood vaccinations and examined sociodemographic correlates of delayed and missing vaccinations. METHODS Datasets from the 2005-7 Multiple Indicator Cluster Surveys from 31 countries were used. Information on vaccinations was based on vaccination cards. Survival analysis was applied to assess(More)
Delayed vaccination against childhood diseases may lead to increased mortality and morbidity among children and also affect the fraction of vaccinated population necessary for elimination of a disease. The purpose of this study was to assess the extent of the delay in vaccinations in four countries belonging to Commonwealth of Independent States and to(More)
OBJECTIVE Amyloid deposition in multiple myeloma (MM) may lead to an arthropathy resembling rheumatoid arthritis (RA). Since a systematic description of its natural history is lacking, we have performed a systematic analysis of all published cases. METHODS Literature review featuring backward and forward database searches and direct inspection of(More)
Immunohistochemical synovial tissue biomarkers are used increasingly to classify arthropathies, study their pathogenesis, and to measure disease activity in clinical trials. We have used receiver operating characteristic (ROC) analysis to quantify the discriminatory abilities of markers for common inflammatory cells (subintimal CD15, CD68, CD3, CD20, CD38,(More)
Population-based epidemiological studies on infectious diseases are limited by methodological problems that may not be encountered in other fields of epidemiology. The acute or asymptomatic nature of many infections hinders a timely diagnosis by trained personnel in a study centre, indicating the need for new collection methods of biological specimens. One(More)
We aimed to evaluate the fraction of exhaled nitric oxide (FENO50) and deaerated exhaled breath condensate pH (dEBCpH) as non-invasive markers of subclinical airway inflammation in pediatric patients with rheumatologic disorders. We determined FENO50 and dEBCpH in a prospective study spanning at least 12 months, comprising 85 pediatric patients with(More)