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1. A fluorescence microscope was used in order to detect whether fluorescent dyes can quickly diffuse into and out of certain parts of single muscle fibres of the frog.2. Several fluorescent dyes entered a system arranged at the centre of each I-band without entering the main part of the fibre.3. The dyes quickly diffused out of the fibres on washing,(More)
Female moths of many species in Geometridae, Arctiidae and some other macrolepidopteran families produce epoxy pheromones, which are probably derived from polyunsaturated hydrocarbons. In order to understand a biosynthetic site, hemolymph from both sexes of two geometrid species, Ascotis selenaria cretacea and Hemerophila artilineata, and one arctiid(More)
Prostaglandin E2 (PGE2) was shown to induce neuronal death in the CNS. To characterize the neurotoxicity of PGE2 and E-prostanoid receptors (EP) in motor neurons, we investigated PGE2-induced cell death and the type(s) of EP responsible for mediating it in NSC-34, a motor neuron-like cell line. Immunoblotting studies showed that EP2 and EP3 were dominantly(More)
Simple organic salts such as (Li(+))(m-IBA) (1), (Na(+))(m-IBA) (2), (K(+))(m-IBA) (3), (Rb(+))(m-IBA) (4), and (Cs(+))(m-IBA) (5) (m-IBA = m-iodobenzoate) were shown to form a mesophase before crystal melting or decomposition. The crystals were obtained in the hydrated form, e.g., 1·(H2O), 2·(H2O), 3·0.5(H2O), 4·(H2O), and 5·(H2O); they were then converted(More)
Amyotrophic lateral sclerosis (ALS) is an adult-onset, progressive, and fatal neurodegenerative disease caused by selective loss of motor neurons. Both ALS model mice and patients with sporadic ALS have increased levels of prostaglandin E2 (PGE2). Furthermore, the protein levels of microsomal PGE synthase-1 and cyclooxygenase-2, which catalyze PGE2(More)
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