Manal M. Gabriel

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Pure silver-, silver oxide- and silver chloride-treated surfaces in comparison to polypropylene inhibited both growth and adherence from saline ofSerratia marcescens, Staphylococcus epidermidis, Pseudomonas aeruginosa andCandida albicans. These same organisms demonstrated enhanced adherence to an Ion-Beam-Assisted-Deposited silver surface followed by loss(More)
Cells of Pseudomonas aeruginosa were adhered to polymethyl methacrylate, polyvinyl acetate, polyvinyl chloride, polyhydroxyethyl methacrylate, mixed-acrylic, silicone, and natural latex materials. Planktonic bacteria and bacteria that adhered to the test materials were compared for their uptake of either L-[3,4,5-3H] leucine or [methyl-3H] thymidine during(More)
Strains of Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Enterococcus faecalis, and Klebsiella pneumoniae, mostly from complicated urinary tract infections, showed reduced adherence to silver-treated silicone or latex catheters as compared with latex or silicone catheters. The relative degrees of cell adherence to catheters at 2 h or 18 h, as(More)
PURPOSE To compare the relative degrees of adherence of a clinical strain of Pseudomonas aeruginosa to the optic material of four intraocular lenses (IOLs). SETTING Center for Applied and Environmental Microbiology, Georgia State University, Atlanta, Georgia, USA. METHODS Intraocular lens optics made of poly(methyl methacrylate) (PMMA), AcrySof-acrylic,(More)
Pseudomonas aeruginosa is a leading cause of human morbidity and mortality that often targets epithelial surfaces. Host immunocompromise, or the presence of indwelling medical devices, including contact lenses, can predispose to infection. While medical devices are known to accumulate bacterial biofilms, it is not well understood why resistant epithelial(More)
PURPOSE Bacterial strains with known capability to bind to hydrogel lenses were examined for their relative capacities to attach irreversibly to a hydrogel contact lens in pure and mixed cultures. METHODS AND RESULTS Time course studies of adhesion through adenosine triphosphate (ATP) or radiolabel analyses indicated that primary adhesion by Pseudomonas(More)
Bacteria commonly associated with nosocomial urinary tract infections were examined in vitro for their relative adherence to latex, 100% silicone-, hydrogel-coated latex-, and hydrogel/silver-coated latex urinary catheters. Degrees of adherence within 2 h were determined with cells radiolabeled with leucine. Adherence was greatest and equivalent on silicone(More)
PURPOSE To examine the early host response to Pseudomonas aeruginosa challenge in the extended contact lens-wearing rat model. METHODS Lewis rats were fitted with extended-wear lotrafilcon A hydrogel lenses in the left eye, and the right eye served as the control. Bacterial challenge was initiated in the experimental eye by fitting a bacteria-soaked(More)