Manabu Okajima

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We investigated the effects of anticancer agents on peripheral blood mononuclear cells for the purpose of providing data to support new translational chemoimmunotherapy regimens. Peripheral-blood mononuclear cells were treated with one of four anticancer agents (5-fluorouracil, irinotecan, cisplatin, and gemcitabine) for 2 h, after which cell viability was(More)
Intr Serial Procalcitonin (PCT) measurement has become a part of routine Intensive care unite (ICU) practice to monitor infections. Tracheostomy is one of the most common surgical procedures in ICU. In addition to procedure itself, complications of tracheostomy such as hemorrhage, airway complications, and pneumothorax may have an influence on daily PCT(More)
Epithelial-mesenchymal transition (EMT) plays a crucial role in cancer metastasis. In this study, we evaluated the effect of heat treatment on tumor growth factor-β1 (TGF-β1)-induced EMT in pancreatic cancer cells and tried to ascertain the mechanism related to any observed effects. Human pancreatic cancer cell lines (BxPC-3, PANC-1 and MIAPaCa-2) were(More)
  • Asano H Stark, Gottlieb T Baker, C Hermann, Howland P Houk, Northrup Xix Nelson, Neurology +18 others
  • 2009
The use of programmed digital computers as general pattern classification and recognition devices is one phase of the current lively interest in artificial intelligence. It is important to choose a class of signals which is, at present, undergoing a good deal of visual inspection by trained people for the purpose of pattern recognition. In this way(More)
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