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To develop a molecular probe for MRI detection of human tumor telomerase reverse transcriptase (hTERT) mRNA expression. Uniformly phosphorothioate-modified hTERT antisense oligonucleotide (ASON) homing hTERT mRNA was labeled with gadolinium (Gd) through the bifunctional chelator 1,4,7, 10-tetraazacyclododecane-N, N', N'', N'''-tetraacetic acid (DOTA)(More)
Adhesive capsulitis (AC) is a painful and disabling disorder, which caused restricted motion and chronic pain of shoulder. Intracavitary contrast-enhanced ultrasound has been recently applied to assess obstructive bile duct diseases, tubal patency, vesicoureteric reflux and so on. The aim of this study was to detect the value of US-arthrography by injecting(More)
OBJECTIVE In this study, we present the design, fabrication, and evaluation of a curved-array-based photoacoustic imaging system designed for imaging vasculatures inside human finger joints with multispectral strategy. METHODS The transducers was fabricated with polyvinylidene fluoride (PVDF) film with a size of 30 mm×2.8 mm, and a curvature radius of 82(More)
Flower opening is essential for pollination and thus successful sexual reproduction; however, the underlying mechanisms of its timing control remain largely elusive. We identify a unique cucumber (Cucumis sativus) line '6457' that produces normal ovaries when nutrients are under-supplied, and super ovaries (87%) with delayed corolla opening when nutrients(More)
OBJECTIVE The purpose of this retrospective study is to evaluate the diagnostic value of contrast enhanced sonography plus gastric distention sonography, the Double Contrast-enhanced Ultrasound (DCUS) in gastric lesions. METHODS 107 cases with pathology confirmed gastric lesions were retrospectively reviewed, DCUS and oral contrast agent ultrasound (US)(More)
PURPOSE Kallikrein is considered as a mediator of tumorigenesis. Various studies examing the relationship between high kallikrein expressions with the clinical outcome in patients with ovarian cancer have yielded controversial conclusions. METHODS We conducted a meta-analysis of 10 studies (N=1478) that evaluated the relationship between positive(More)
Fetal intra-abdominal umbilical vein varix is a rare condition characterized by focal dilatation of the umbilical vein of the fetus. We report a case of fetal intra-abdominal umbilical vein varix associated with additional sonographic abnormalities and detected at 31 weeks' gestation. Several follow-up sonographic examinations were performed, and the(More)
OBJECTIVE To explore the role of the abnormal expression of miRNAs in the development process of non-small cell lung cancer and the feasibility of ultrasound microbubble-mediated gene therapy after transfecting antisense miRNA-224 and miRNA-122a plasmids into non-small cell lung cancer A549 cells. METHODS Antisense miRNA-224 and miRNA-122a plasmids were(More)
This study was aimed to evaluate the quantitative analysis of MCE in diagnosing coronary atherosclerotic heart disease. MCE was performed on 10 patients with coronary artery disease. The parameters were extracted from imaging during the refilling period by time-intensity curve. SIpeak represents the peak of the signal intensity at the end of the perfusion(More)