Mamle Quarmyne

Learn More
The mechanisms which regulate HSC regeneration following myelosuppressive injury are not well understood. We identified epidermal growth factor (EGF) to be highly enriched in the bone marrow (BM) serum of mice bearing deletion of Bak and Bax in Tie2 + cells (Tie2Cre;Bak1 −/− ;Bax fl/− mice), which displayed radioprotection of the HSC pool and 100% survival(More)
  • 1