Mamidou Witabouna Koné

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A total of 148 crude ethanol extracts from 115 plant species were tested in vitro against Gram-negative strains (Escherichia coli, Pseudomonas aeruginosa) and the Gram-positive Staphylococcus aureus and Enterococcus faecalis. Moreover, they were submitted to antifungal assays against Candida albicans and Cladosporium cucumerinum, a human and a plant(More)
BACKGROUND & OBJECTIVES Mosquitoes increased resistance to insecticides, and environmental concerns about the use of insecticides, pose a major challenge in the search for new molecules to deplete and incapacitate mosquito populations. Plants are the valuable source as practices consisting in exploiting plant materials as repellents, and are still in wide(More)
Purpose: To synthesize hybrid benzimidazolyl-chalcone derivatives, evaluate their anthelmintic activity, and establish some structural elements which could lead to induction and enhancement of this activity. Methods: A series of 1-(1H-benzimidazol-2-yl)-3-aryl-2-propen-1-one compounds (6a-z) was synthesized by condensation reaction of 2-acetylbenzimidazole(More)
An annual 20% excess mortality rate is observed in HIV-seropositive patients after treatment for tuberculosis. An affordable secondary prophylaxis against main opportunistic diseases is needed, i.e. against tuberculosis, toxoplasmosis, pneumocystosis and other infections occurring in this target population. This open prospective randomized study assessed(More)
The antitrypanosomal activity of 101 crude ethanol extracts derived from 88 medicinal plants from Côte d'Ivoire was determined in vitro using Trypanosoma brucei rhodesiense. Of those extracts 8 showed good activity (IC50 values < or =8 microg/ml), 37 revealed a weak activity (IC50 values between 25 and 8.1 microg/ml) and 56 did not show any activity at all(More)
BACKGROUND Due to their genetic proximity, chimpanzees share with human several diseases including bacterial, fungal and viral infections, such as candidiasis, acquired immune deficiency syndrome (AIDS), Ebola virus disease. However, in its natural environment, chimpanzees are tolerant to several pathogens including simian immunodeficiency virus (SIV),(More)
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