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Proteomic Analysis of Phagocytosis in the Enteric Protozoan Parasite Entamoeba histolytica
ABSTRACT Proteomic analysis of phagosomes isolated from Entamoeba histolytica by liquid chromatography and mass spectrometry identified 85 proteins involved in surface recognition, actin cytoskeletonExpand
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Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis.
The protozoan parasite Entamoeba histolytica ingests and feeds on microorganisms and mammalian cells. Phagocytosis is essential for cell growth and implicated in pathogenesis of E. histolytica. WeExpand
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Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome.
A genome-wide transcriptional analysis of Entamoeba histolytica was performed on trophozoites isolated from the colon of six infected mice and from in vitro culture. An Affymetrix platform geneExpand
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Plasmodium falciparum FIKK Kinase Members Target Distinct Components of the Erythrocyte Membrane
Background Modulation of infected host cells by intracellular pathogens is a prerequisite for successful establishment of infection. In the human malaria parasite Plasmodium falciparum, potentialExpand
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New insights into molecular mechanisms of phagocytosis in Entamoeba histolytica by proteomic analysis.
The protozoan parasite Entamoeba histolytica ingests microorganisms and mammalian cells. Phagocytosis is essential for cell growth and is implicated in pathogenesis of E. histolytica. PhagocytosisExpand
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Metallothionein-1 Isoforms and Vimentin Are Direct PU.1 Downstream Target Genes in Leukemia Cells*
PU.1 is a key transcription factor for hematopoiesis and plays important roles in various hematological malignancies. To clarify the molecular function of PU.1, we initially tried to identify bonaExpand
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Two cysteine protease inhibitors, EhICP1 and 2, localized in distinct compartments, negatively regulate secretion in Entamoeba histolytica
The enteric protozoan parasite Entamoeba histolytica uniquely possesses two isotypes of ICPs, a novel class of inhibitors for cysteine proteases. These two EhICPs showed a remarkable difference inExpand
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Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface.
The cross-linking of elastin by lysyl oxidase (LOX) family members is essential for the integrity and elasticity of elastic fibers, which play an important role in the characteristic resilience ofExpand
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Polyamine Distribution Profiles among Some Members within Delta-and Epsilon-Subclasses of Proteobacteria
Cellular polyamines of 18 species(13 genera)belonging to the delta and epsilon subclasses of the class Proteobacteria were analyzed by HPLC and GC. In the delta subclass, the four marineExpand
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