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Stability-indicating determination of meropenem in presence of its degradation product.
TLDR
The indication of stability has been undertaken under conditions likely to be expected at normal storage and among the analytical techniques adopted for quantification are spectrophotometry, first-derivative of ratio spectra, as well as chromatography. Expand
Selective determination of ertapenem in the presence of its degradation product.
TLDR
Stability-indicative determination of ertapenem (ERTM) in the presence of its beta-lactam open-ring degradation product, which is also the metabolite, is investigated and the indication of stability has been undertaken under conditions likely to be expected at normal storage conditions. Expand
Simultaneous determination of sitagliptin and metformin in their pharmaceutical formulation.
TLDR
The proposed methods were successfully applied to the analysis of sitagliptin phosphate and metformin hydrochloride in bulk form and in their pharmaceutical formulation without interference from other additives. Expand
Novel spectrophotometric methods for simultaneous determination of timolol and dorzolamide in their binary mixture.
TLDR
Two smart and novel spectrophotometric methods were developed and validated for the determination of a binary mixture of timolol maleate and dorzolamide hydrochloride in presence of benzalkonium chloride without prior separation, using unified regression equation. Expand
Development of a sensitive UPLC-ESI-MS/MS method for quantification of sofosbuvir and its metabolite, GS-331007, in human plasma: Application to a bioequivalence study.
TLDR
A rapid and simple LC-MS/MS method was developed and validated for the simultaneous estimation of sofosbuvir (SF) and its metabolite GS-331007 (GS) using famotidine as an internal standard (IS) and successfully applied to a bioequivalence study in human volunteers. Expand
Quantification of sofosbuvir and ledipasvir in human plasma by UPLC-MS/MS method: Application to fasting and fed bioequivalence studies.
TLDR
The developed rapid and sensitive LC-MS/MS method was successfully applied to both fasting and fed bioequivalence studies in healthy human volunteers and results were within the acceptable limits. Expand
Novel determination of sofosbuvir and velpatasvir in human plasma by UPLC-MS/MS method: Application to a bioequivalence study.
TLDR
The developed method was successfully utilized for estimating both SOF and VEL in the plasma of healthy human volunteers participated in a bioequivalence study. Expand
Multi-residues determination of antimicrobials in fish tissues by HPLC-ESI-MS/MS method.
TLDR
The developed LC-MS/MS method was successfully applied for the detection of antimicrobials in real fish tissue samples obtained from different fish farms and the precision and accuracy of the results were within the acceptable limits. Expand
Chromatographic Determination of Cyclopentolate Hydrochloride and Phenylephrine Hydrochloride in the Presence of Their Potential Degradation Products.
Two sensitive, selective, and precise stability-indicating methods have been developed for the simultaneous determination of the active pharmaceutical ingredients cyclopentolate hydrochloride (CLO)Expand
Comparative Study of Different Ionophores in Ion Selective Electrodes for Stability indicating Determination of Moxifloxacin
Three novel moxifloxacin (MO) selective electrodes were investigated with 2-nitrophenyl octyl ether as a plasticizer in a polymeric matrix of polyvinyl chloride (PVC). Sensor 1 was fabricated usingExpand
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