Mamdouh A K Sedhom
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Objective Inflammatory bowel diseases (IBD) have been intrinsically linked to a deregulated cytokine network, but novel therapeutic principles are urgently needed. Here we identify the interleukin… Continue Reading
Objectives A previously identified signal transduction and activator of transcription-3 (STAT3) target-enriched gene signature in circulating CD4+ T cells of patients with early rheumatoid arthritis… Continue Reading
Diabetes mellitus is a common disease of cats and is similar to type 2 diabetes (T2D) in humans, especially with respect to the role of obesity-induced insulin resistance, glucose toxicity, decreased… Continue Reading
Introduction Novel therapeutic principles are urgently needed to cure inflammatory bowel diseases (IBD) that have been intrinsically linked to a deregulated inflammatory cytokine network. Here we… Continue Reading
Airway exposure to endotoxin and other microbial TLR agonists induces a rapid production of mediators including IL-1 and IL-17, neutrophil recruitment, and bronchoconstriction which are abrogated in… Continue Reading