Malvern Munjoma

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We determined the utility of an assay for 13 cancer-associated HPV types in primary cervical cancer screening of Zimbabwe women at high risk of HIV infection. HIV antibody status was determined by ELISA of oral mucosal specimens, and HPV DNA in the genital tract was identified by hybridization of cervical scrapes with probe B of Hybrid Capture II. Among the(More)
OBJECTIVE To describe the methodological challenges of a nine months follow up study of mothers recruited from a national Prevention of Mother To Child Transmission (PMTCT) programme with regards to defaulters, drop outs and compliance. DESIGN Nested case control study. SETTING Three peri-urban clinics in Zimbabwe namely: Epworth, St Mary's, Seke North.(More)
BACKGROUND Complete follow up is an essential component of observational cohorts irrespective of the type of disease. OBJECTIVES To describe five years follow up of mother and child pairs on a PMTCT program, highlighting loss to follow up (LTFU) and mortality (attrition). STUDY DESIGN A cohort of pregnant women was enrolled from the national PMTCT(More)
Maternal human immunodeficiency virus (HIV) RNA load, vertical transmission of subtype C HIV, and infant mortality were examined in 251 HIV-seropositive women and their infants in Zimbabwe. Demographic characteristics, health and medical histories, serum HIV RNA loads, and CD4+ lymphocyte counts for mothers were examined by logistic regression analysis to(More)
OBJECTIVE.: To compare the treatment outcome of cervical intraepithelial neoplasia (CIN 2,3) on HIV-infected and uninfected women treated by cryotherapy or loop electrosurgical excision procedure (LEEP). METHODS.: A total of 147 women were recruited into the study between April 1997 and May 1998. Cryotherapy was performed in 75 women and LEEP in 72 women(More)
Stool specimens were collected from 1995 sugarcane cutters on the Hippo Valley and Triangle sugar estates, Zimbabwe, in order to determine the prevalence and intensity of Schistosoma mansoni infection. Pathological changes normally ascribed to S. mansoni infection were assessed in the infected cutters, by ultrasonography before treatment. The height,(More)
Ultrasound was used to diagnose periportal fibrosis (PPF) in a rural Zimbabwean community where Schistosoma mansoni is endemic. Ultrasound findings were compared with stool microscopy and abdominal palpation in 492 adults (305 females). 47 (9.6%) had definite PPF. The prevalence of PPF increased with age (P < 0.001), while S. mansoni egg counts decreased(More)
A cross-sectional study at two urban primary health care clinics in Zimbabwe was conducted among 393 consecutive women. The purpose was to determine the seroprevalence of herpes simplex virus type 2 (HSV-2), to identify coinfections and to determine the association between HSV-2, HIV and other sexually transmitted infections (STIs). Sera were tested for(More)
Transmission of human immunodeficiency virus (HIV) and mortality was studied among infants of infected women in Zimbabwe. Of 367 infants born to HIV-infected women, 72 (19.6%) died compared with 20 (5.4%) of 372 infants of uninfected women (P < .01). Infection by HIV DNA polymerase chain reaction among infants who survived >7 days and died within 2 years(More)
Quantitative determination of Schistosoma mansoni infection was carried out on 1995 cane cutters of the Hippo Valley and Triangle Sugar Estates. A total of 315 cutters were chosen for the study on the basis of S. mansoni infection and lack of anti-schistosomal chemotherapy during the previous three years. Stool consistency and blood and mucus in stool were(More)