Malorie E. Watson

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The discriminative ability of several skeletal and tumour markers was assessed in 102 patients with prostatic disease. These comprised serum acid and alkaline phosphatase, serum albumin and osteocalcin, urinary excretion of calcium, hydroxyproline and 6-oxo prostaglandin F1 alpha. None of the tests was of value in distinguishing patients with benign(More)
To determine the fractional delivered oxygen concentrations (FDO2) and the proper functioning of patient valves in adult resuscitation bags, we studied the Laerdal, the PMR 1, the PMR 2, and the Vitalograph resuscitators at various oxygen flowrates and ventilation patterns, with and without reservoirs. The Vitalograph, with new or old reservoir, and the PMR(More)
Transient systolic hypertension, particularly during the 6 hours after operation, was found to be a significant complication in a series of33 consecutive cases ofaortic valve replacement. This rise in systolic blood pressure occurred in spite of treatment and was more common in cases ofpredominant aortic stenosis. It was not found after mitral valve(More)
This report describes a case in which puncture of the brachial artery to obtain a sample for blood-gas analysis resulted in damage to the median nerve with a persisting neuropathy and apparent loss of function. Errors in judgment and contributions to possible negligence included (1) inappropriate choice of sampling site; (2) lack of knowledge of precautions(More)
Clodronate disodium (dichloromethylene diphosphonate), a specific inhibitor of bone resorption, was given by mouth (1.0-3.2 g daily) to nine patients with primary hyperparathyroidism for two to 32 weeks so that its clinical and metabolic effects could be evaluated. Bone resorption decreased in all patients as judged by a fall in the fasting urinary calcium(More)
We describe a patient with metastatic carcinoma of the prostate associated with paraplegia. The patient also had Paget's disease of bone elsewhere. Because the neurological lesion was thought to be due to Paget's disease, the patient was treated with inhibitors of bone resorption. Treatment rapidly induced clinical remission and inhibition of bone(More)
When correction was made for hypoalbuminaemia, 23 of 50 ambulant patients with definite or classical rheumatoid arthritis were found to have hypercalcaemia. When these 23 patients were studied 6 months later, 7 had hypercalcaemia as defined by the correction factor for a low serum albumin level, and 6 of these patients had raised serum ionised calcium(More)