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Primary cilium formation requires von hippel-lindau gene function in renal-derived cells.
Biallelic inactivation of the von Hippel-Lindau tumor suppressor gene, VHL, occurs in the majority of renal clear cell carcinomas (RCC). VHL's function, regulating the degradation ofExpand
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Proteasome Mutants , pre 4-2 and ump 1-2 , Suppress the Essential Function but Not the Mitochondrial RNase P Function of the Saccharomyces cerevisiae Gene RPM 2
The Saccharomyces cerevisiae nuclear gene RPM2 encodes a component of the mitochondrial tRNAprocessing enzyme RNase P. Cells grown on fermentable carbon sources do not require mitochondrial tRNAExpand
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