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IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
Somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 occur in gliomas and acute myeloid leukaemia (AML). Since patients with multiple enchondromas have occasionally been reported to haveExpand
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Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
Ollier disease and Maffucci syndrome are characterized by multiple central cartilaginous tumors that are accompanied by soft tissue hemangiomas in Maffucci syndrome. We show that in 37 of 40Expand
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Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2
Isocitrate dehydrogenase (IDH) genes 1 and 2 are frequently mutated in acute myeloid leukaemia (AML), low-grade glioma, cholangiocarcinoma (CC) and chondrosarcoma (CS). For AML, low-grade glioma andExpand
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Electroporation in combination with a plasmid vector containing SV40 enhancer elements results in increased and persistent gene expression in mouse muscle.
Gene transfer into muscle upon injection of plasmid DNA is feasible but occurs with low frequency. However, by using electroporation after injection of plasmid DNA into mouse muscle it has beenExpand
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Combination of angiopoietin-1 and vascular endothelial growth factor gene therapy enhances arteriogenesis in the ischemic myocardium.
We hypothesised that angiopoietin-1 (Ang-1), in conjunction with vascular endothelial growth factor (VEGF) gene therapy, can enhance arteriogenesis and angiogenesis during myocardial ischemia. MiceExpand
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Coexisting NRAS and BRAF mutations in primary familial melanomas with specific CDKN2A germline alterations.
To the Editor Germline aberrations in the CDKN2A gene are observed in some melanoma-prone families and represent high penetrance mutations (Hussussian et al., 1994; Kamb et al., 1994). INK4A (p16)Expand
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Nonsurgical Direct Delivery of Plasmid DNA Into Rat Heart: Time Course, Dose Response, and the Influence of Different Promoters on Gene Expression
Transfer of genes encoding therapeutic proteins into the myocardium shows great potential for treatment of coronary artery disease. To quantitatively elucidate the behavior of plasmid DNA followingExpand
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Some Metabolic Effects of Three Different Rations Following Laparotomy in Sheep
Abstract Mohebbi, M., Meimandi, A.H. and Eskandarpour, M. 2002. Some metabolic effects of three different rations following laparotomy in sheep. J. Appl. Anim. Res., 22: 237–242. To evaluate theExpand