Malgorzata Markiewicz

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Transforming growth factor-beta (TGF-beta) and connective tissue growth factor (CTGF) are ubiquitously expressed in various forms of tissue fibrosis, including fibrotic diseases of the kidney. To clarify the common and divergent roles of these growth factors in the cells responsible for pathological extracellular matrix (ECM) deposition in renal fibrosis,(More)
INTRODUCTION The mortality rate associated with UGI bleeding remains high at 7-14%. Pharmacologic and endoscopic interventions are the current standard treatment, but there are few alternative options should these fail. This study aimed to assess the efficacy and safety of recombinant activated factor VII (rFVIIa) in the rescue treatment of severe upper(More)
The presence of the HLA-B35 allele has emerged as an important risk factor for the development of isolated pulmonary hypertension in patients with scleroderma, however the mechanisms underlying this association have not been fully elucidated. The goal of our study was to determine the molecular mechanisms that mediate the biological effects of HLA-B35 in(More)
BACKGROUND/PURPOSE The aim of the study was to analyze changing management and survival of children with hepatoblastoma (HBL) treated in one center. MATERIALS AND METHODS Over the last 20 years, 51 children with HBL were treated. Surgery was performed in 48 children (94.1%), conventional liver resection in 38 (of those, 2 received a rescue liver(More)
ELIZABETH GORE-HYER,1 DANIEL SHEGOGUE,1 MALGORZATA MARKIEWICZ,1 SHIANLEN LO,1 DEBRA HAZEN-MARTIN,2 EDDIE L. GREENE,3 GARY GROTENDORST,4 AND MARIA TROJANOWSKA1 Divisions of 1Rheumatology and Immunology and 3Nephrology, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425; and 4Department of(More)
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