Malgorzata Dytko

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BACKGROUND Cognitive impairment and dementia has been reported in autosomal dominant hereditary spastic paraparesis (HSP) linked to the SPG4 locus. There has only been one postmortem examination described; not all accept that progressive cognitive decline is a feature of this disorder. OBJECTIVE A family with SPG4-HSP known to have a deletion of exon 17(More)
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