Malcolm R. Waterfield

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This prospective multi-centre true two-sided equivalence trial was designed to test the clinical equivalence of open (ASCP) and laparoscopic (LSCP) sacrocolpopexy using objective and subjective outcomes The study was carried out in three urogynaecology units in England, UK and the patient population consisted of women referred with symptomatic and(More)
Objective: To test whether cannabinoids reduce urge incontinence episodes without affecting voiding in patients with multiple sclerosis. This was part of the multicentre trial of the Cannabinoids in Multiple Sclerosis (CAMS) study. Subjects and methods: The CAMS study randomised 630 patients to receive oral administration of cannabis extract,(More)
OBJECTIVE To test whether supervised pelvic floor exercises antenatally will reduce the incidence of postpartum stress incontinence in at-risk primigravidae with bladder neck mobility, ultrasonically proven. DESIGN Single blind, randomised controlled trial. SETTING Antenatal clinic in a UK NHS Trust Hospital. SAMPLE Two hundred and sixty-eight(More)
It is thought that antenatal pelvic floor muscle training (PFMT) might produce a strong pelvic floor resulting in prolonged labour, whilst some believe it produces well-controlled muscles that facilitate rotation of the foetal head and shortens the duration of labour. This secondary analysis (of a previously published randomised controlled trial) assesses(More)
OBJECTIVE To determine the long-term effectiveness of antenatal pelvic floor muscle training (PFMT) on stress urinary incontinence (SUI). DESIGN Eight-year follow up of a randomised controlled trial (RCT). SETTING Acute NHS Teaching Trust. POPULATION Participants in an RCT of antenatal PFMT 8 years previously. METHOD Participants were asked about(More)
There seems to be a temporal association between increasing use of “hands off” the perineum in labour and reduced use of episiotomy with an increasing rate of anal sphincter injuries. We aimed to determine how common the practice of “hands off” the perineum is. An observational postal questionnaire study of 1,000 midwives in England in which the main(More)
The purpose of this study was to investigate the defects associated with cystocoele and the outcome of anterior repair. Prospective study using POPQ and MRI before and after surgery. Seventy women completed 1 year follow-up with anatomical and subjective failure rates of 51% and 32%, respectively. MRI features suggestive of central fascial defects were(More)
This study was performed to determine whether anatomical recurrence of cystocoele 1 year after anterior vaginal repair is related to biomechanical properties and/or the content of collagen in the vaginal wall and epithelial tissues. In this prospective, observational study in a UK teaching hospital, we assessed women undergoing surgery for symptomatic(More)
The deoxyribonucleic acid (DNA) content of sputum from cystic fibrosis patients was examined to establish if it was likely to be a useful indicator of worsening clinical condition. The assay was reproducible (coefficient of variation 4.2%) and added DNA could be demonstrated. Added antibiotics did not influence the result. The daily DNA content in the(More)
The objectives of this prospective study were to determine the prevalence of pelvic organ prolapse (POP) after colposuspension and to investigate possible preoperative and operative risk factors. Seventy-seven women who underwent colposuspension between 1996 and 1997 were investigated. POP was assessed before colposuspension using the pelvic organ prolapse(More)