Malcolm Meistrell

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To elucidate endogenous mechanisms underlying cerebral damage during ischemia, brain polyamine oxidase activity was measured in rats subjected to permanent occlusion of the middle cerebral artery. Brain polyamine oxidase activity was increased significantly within 2 h after the onset of ischemia in brain homogenates (15.8 +/- 0.9 nmol/h/mg protein) as(More)
BACKGROUND Nitric oxide (NO), a small effector molecule produced enzymatically from L-arginine by nitric oxide synthase (NOS), is a mediator not only of important homeostatic mechanisms (e.g., blood vessel tone and tissue perfusion), but also of key aspects of local and systemic inflammatory responses. Previous efforts to develop inhibitors of NOS to(More)
This study examined the effect of lingual root torque during the third stage of Begg treatment upon the maxillary central incisor, hard-tissue Point A, and soft-tissue Point A. Lateral cephalograms were taken, at the beginning and end of Stage III, of eighteen patients undergoing Begg treatment. Linear and angular measurements were made in an attempt to(More)
The reliability of a commercially available computer prediction program (Quick Ceph II) was evaluated using pretreatment and posttreatment cephalograms of 30 patients who were treated during an active period of growth. The computer prediction was compared with the actual treatment result, and the growth forecast with the computer program was compared with(More)
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