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Little is known about the neuronal mechanisms underlying the temporal ordering of tactile signals. We examined the brain regions involved in judgments of the temporal order of successive taps delivered to both hands. Participants received identical stimuli while engaging in 2 different tasks: Judging the temporal order and judging the numerosity of points(More)
It is generally accepted that the brain can resolve the order of two stimuli that are separated in time by 20-50 ms. This applies to temporal order judgment of two tactile stimuli, delivered one to each hand, as long as the arms are uncrossed. However, crossing the arms caused misreporting (that is, inverting) of the temporal order. The reversal was not due(More)
We examined effects of handedness on the judgment of temporal order of successive taps delivered to both hands. When the subjects' arms were uncrossed, the temporal resolution (84% correct responses) of right-handed subjects (52 +/- 4 ms, n = 16) was significantly better than that of left-handed subjects (83 +/- 9 ms, n = 16). When their arms were crossed,(More)
A temporal order judgment task was developed for mice. After training male mice (C57BL6NCrj, n=15) to poke their noses into a hole, two stimuli (brief puffs of air) were delivered to the whiskers with a fixed interval of 750 ms in one of four orders: right (R)-left (L), L-R, L-L, and R-R. The mice were rewarded when they oriented their heads toward the(More)
The neuronal mechanisms for ordering sensory signals in time still need to be clarified despite a long history of research. To address this issue, we recently developed a behavioral task of temporal order judgment in mice. In the present study, we examined the expression of c-Fos, a marker of neural activation, in mice just after they carried out the(More)
We developed a new method for comparing immunopositive cell densities across groups of animals and creating statistical parametric maps on standardized sections. As an example, we compared Iba-1 (microglial marker) positive cell densities in rats with (n=6) and without (n=6) unilateral injection of 1-methyl-4-phenylpyridinium salt (MPP+). Immunopositive(More)
Adopting an unusual posture can sometimes give rise to paradoxical experiences. For example, the subjective ordering of successive unseen tactile stimuli delivered to the two arms can be affected when people cross them. A growing body of evidence now highlights the role played by the parietal cortex in spatio-temporal information processing when sensory(More)
Altered multisensory integration has been reported in autism; however, little is known concerning how the autistic brain processes spatio-temporal information concerning tactile stimuli. We report a study in which a crossed-hands illusion was investigated in autistic children. Neurotypical individuals often experience a subjective reversal of temporal order(More)
The existence of wireless and mobile technology has provided opportunities to support learning regardless of the physical learning space. Thus, usage of mobile terminals such as smart PDA (personal digital assistant) in a learning system is very common phenomenon. Mobile devices can communicate with wireless mobile terminal and realize the intelligence(More)