Makoto Fujisaki

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OBJECTIVE Current fetal cardiac intervention for restrictive atrial septum is invasive and technically demanding. We investigated the feasibility of computer-assisted high-intensity focused ultrasound (HIFU) for cardiac intervention on the atrial septum of a beating heart. METHODS To create an interatrial communication in the beating heart of nine(More)
Dihydrotestosterone (DHT), a biologically active metabolite of testosterone, may be misused in sports to benefit from its anabolic and psychotropic effects. After DHT application, a significant increase of the glucuronides of DHT and its metabolites can be expected for a certain time period depending upon dose, formulation, route of administration, and in(More)
We have previously reported that the urine of patients with Cushing's syndrome, including pituitary adenoma cases and adrenal adenoma cases, consistently show a conspicuous peak in the chromatographical analysis of 17-ketosteroid fraction but not in the urine of control subjects. The substance emerges just before 11beta-hydroxy-androsterone (11beta-OH-A) in(More)
Vitamin-enriched, lyophilized serum (VES) was prepared for an inter-laboratory study to compare vitamin assays. The VES contained water-soluble vitamins (vitamin B1, vitamin B12, vitamin C, and folate), fat-soluble vitamins (vitamin A and vitamin E), and cholesterol. We performed stability studies and determined vitamin concentrations and total cholesterol(More)
1-Phenyl-N-methyl-1,2,3,4-tetrahydroisoquinoline and 1-phenyl-1,2,3,4-tetrahydroisoquinoline were detected for the first time in parkinsonian human brain using gas chromatography-tandem mass spectrometry (GC-MS-MS). Since these compounds are structural analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that produces parkinsonism in humans,(More)
infiltrating type of poorly differentiated gastric carcinoma. It is characterized by cancer cell infiltration and proliferation beneath the gastric mucosa with marked stromal fibrosis [1]. The gastric wall is thickened and stiffened due to diffuse in− filtration and proliferation of cancer cells with extensive stromal fibrosis. Endosco− py is useful for(More)
The benefits of motor and mental practice on physical performance have been identified for decades. Here, we used event-related potentials to examine the precise effect of motor practice on the cortical signal during physical performance. Participants were scanned before and after learning, having practiced a particular script in between these two sessions.(More)
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