Makiko Matsumoto

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FTY720 (fingolimod) has demonstrated efficacy in multiple sclerosis (MS). We evaluated the effects of FTY720 on progressive disability, viral load, and antibody responses in mice infected with Theiler's murine encephalomyocarditis virus (TMEV). FTY720 and phosphorylated FTY720 (FTY720-P) were detected in the brain after intraperitoneal injection of the(More)
PURPOSE We investigated succinate metabolism in cells undergoing clinically relevant cyclic stretch and in spontaneously hypertensive rat (SHR) retina. METHODS We seeded ARPE-19 cells on 6-well BioFlex collagen I-coated, silicone elastomer-bottomed culture plates. Cells then were subjected to pulsatile stretch using a computer-controlled vacuum stretch(More)
The International Labour Office welcomes such applications. Libraries, institutions and other users registered with reproduction rights organizations may make copies in accordance with the licences issued to them for this purpose. Visit http://www.ifrro.org to find the reproduction rights organization in your country. The designations employed in ILO(More)
We present a case of cervical varix and low-lying placenta. A cesarean section was performed because of the risk of bleeding with vaginal delivery; hemostasis was achieved using z sutures at the bleeding points. After delivery, the cervical varix decreased dramatically in size. It is important to recognize the clinical features and available treatments for(More)
—Many parameters of wireless communications are uniquely configured, regardless of their communication environments. However, we believe that stations are able to achieve efficiency in communications using surrounding information. One of the systems that is expected to improve the performance of wireless communications is Carrier Sense Multiple Access with(More)
The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) that can perform multiple functions. We determined the usefulness of noninvasive evaluation of proliferative diabetic retinopathy (PDR) pathologies before and after intravitreal injection of bevacizumab (IVB) using the new indirect viewing system of the retro-mode function(More)
Preface Chapter 1 of this thesis has been published in the series Information Modelling and Knowledge Bases, [45]. Chapters 3 and 4 are slightly revised versions of papers written jointly with Marko Junkkari and published in the same series. 1 An earlier version of chapter 2 has been published as a Technical Report. 2 Chapter 5 has been revised from an(More)
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