Claim Your Author Page
Following fertilization in mammals, paternal genomic 5-methyl-2'-deoxycytidine (5 mC) content is thought to decrease via oxidation to 5-hydroxymethyl-2'-deoxycytidine (5 hmC). This reciprocal model… (More)
Mammalian genomes can be edited by injecting pronuclear embryos with Cas9 cRNA and guide RNA (gRNA) but it is unknown whether editing can also occur during the onset of embryonic development, prior… (More)
Sperm are highly differentiated and the activities that reprogram them for embryonic development during fertilization have historically been considered unique to the oocyte. We here challenge this… (More)
This corrects the article DOI: 10.1038/srep07621.
Bacterial artificial chromosomes (BACs) offer a means of manipulating gene expression and tagging gene products in the mammalian genome without the need to alter endogenous gene structure and risk… (More)
Iodine is an essential element for humans; however, it can be toxic depending on its chemical form. A variety of toxic and non-toxic iodine species have been identified in environmental water and in… (More)
The present study proposed a PC time management tool for university students and considered the visualizatien of information from a point of view of communication design, From literature review,… (More)