Majid Taati

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OBJECTIVES The neuroprotective effect of fruit aqueous extract of Ziziphus jujuba Lam on glucose-induced neurotoxicity in PC12 cells as an appropriate in vitro model of diabetic neuropathy was investigated. MATERIALS AND METHODS Cell viability was determined by the MTT assay. Cellular reactive oxygen species (ROS) generation was measured by DCFH-DA(More)
This study was designed to examine the effects of intracerebroventricular injection of DL-AP5 (N-methyl-D-aspartate (NMDA) receptor antagonist) and glutamate on ghrelin-induced feeding behavior in 3-h food-deprived (FD3) broiler cockerels. At first, guide cannula was surgically implanted in the right lateral ventricle of chickens. In experiment 1, birds(More)
Regular exercise has beneficial effects on cerebrovascular diseases; however, its biochemical mechanisms are not fully known. The purpose of this study was to determine antioxidant enzyme activities and lipid peroxidation of both hippocampi after applying exercise followed by occluding one common carotid. Wistar rats were divided into four groups of(More)
In mammals, LPS regulate feeding primarily through the 5-HT1A and 5-HT2c receptors within the brain. However, the central effect of 5-HT1A and 5-HT2c on LPS-induced feeding behavior has not been studied in non-mammalian species. Also, the role of glutamatergic system in LPS-induced anorexia has never been examined in either mammalian or non-mammalian(More)
1 Department of Physiology, School of Veterinary Medicine, Lorestan University, Khoramabad, Iran. 2 Division of Biochemistry, School of Veterinary Medicine, Lorestan University, Khoramabad, Iran. 3 Department of Chemistry, School of Basic Sciences, Lorestan University, Khoramabad, Iran. 4 Razi Herbal Medicines Research Center, Lorestan University of Medical(More)
Ghrelin, the endogenous ligand for growth hormone secretagogue receptor, has been reported to prevent ischemia/reperfusion (I/R) injury in various tissues by its antioxidant activity. Therefore, this study was aimed to investigate the effect of ghrelin on sperm quality and antioxidant enzyme activity in a rat testicular ischemia/reperfusion injury model.(More)
While it is well known that exercise can improve cognitive performance, the underlying mechanisms are not fully understood. There is now evidence that histamine can modulate learning and memory in different types of behavioral tasks. The present study was designed to examine the possible role of central histamine H1 and H2 receptors in forced treadmill(More)
BACKGROUND Testicular torsion is a medical emergency that requires surgical intervention to reperfuse the affected testis. Ischemia reperfusion injury is usually associated with proinflammatory cytokine generation and apoptosis of germ cells in the testes. OBJECTIVE In this study we investigate the effect of ghrelin on the proinflammatory cytokines levels(More)
Ischemia-reperfusion injury is a possible cause of testicular damage and infertility after testicular torsion and detorsion. The purpose of this study was to evaluate the effect of ghrelin on testicular ischemia-reperfusion damage. A total of 30 adult male rats were selected for the study and divided randomly into 3 groups, each containing 10 rats. Animals(More)
To confirm the ethno-therapeutic claims that have been made for Pistacia khinjuk, wound-healing activity and antioxidant activity were studied to understand the mechanism of healing wounds by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, phenol content, total flavonoid content, and total antioxidant capacity. Antibacterial activity of the methanolic(More)