Majid Mumtaz

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Trace elements play an important role in human health and disease. Trace elements participate in tissue, cellular and subcellular function. These include immunoregulation by both humoral and cellular mechanism, nerve conduction, muscle contraction, membrane potential regulation, and mitochondrial activity, among others (1, 2). Although these trace elements(More)
Life-time human health risk of cancer attributed to trihalomethanes in drinking water in an urban-industrialized area of Karachi (Pakistan) was conducted through multiple pathways of exposure. The extent of cancer risk was compared with USEPA guidelines. Human health cancer risk for total trihalomethanes (TTHMs) through ingestion and dermal routes were(More)
The World Health Organization (WHO), Environmental Protection Agency (EPA), and International Atomic Energy Agency (IAEA) have recommended the use of hair for worldwide environmental monitoring. Mercury exposure to the inhabitants of Karachi was assessed by using hair as bioindicator. Hair samples of 200 residents of Karachi were collected and analyzed(More)
Increased bacterial resistance towards commonly used antibiotics has become a debated issue all over the world in a last few decades. Due to this, consumer demand towards natural anti-microbial agents is increasing day by day. Natural anti-microbial agents have gained enormous attention as an alternative therapeutic agent in pharmaceutical industry. Current(More)
Alterations of trace elements and electrolyte levels were investigated in blood of 28 normal subjects and 30 patients with diabetes mellitus. The blood was analyzed for iron, copper, zinc, lead, nickel, chromium, sodium, potassium and calcium. Concentration of chromium, zinc and iron significantly decreased in blood of diabetic patients as compared to(More)
The human digestive tract contains some 100 trillion cells and thousands of species of micro-organisms may be present as normal flora of this tract as well as other mucocutaneous junctions of the body. Candida specie is the most common organism residing in these areas and can easily invade the internal tissues in cases of loss of host defenses.(More)
The ground and municipal water supply samples of Karachi city were analyzed for their fluoride contents. The fluoride contents in water samples collected from the subsurface and river sources were found below the WHO recommended value for the general health of the people. However, in some industrial areas the groundwater sample showed higher level of(More)
The present paper deals with synthesis, characterization and amylase inhibitory activity of pyrazinamide (PYZ) with iron in its both (II) and (III) oxidation states. The synthesized complexes were characterized on the basis of IR, UV, 1H-NMR, 13C-NMR, elemental analysis and SEM. Changes in IR data shows that PYZ form complex with octahedral geometry and(More)
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