Majeed M Ibrahim

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OBJECTIVE We aimed to investigate the effect of ghrelin antagonist (D-Lys3) GHRP-6 on the treatment of ovariectomy-induced obesity as compared to hormone replacement therapy with estradiol. METHODS Twenty eight rats were divided into four groups: control sham operated (C), ovariectomized non-treated (OVX), ovariectomized+estradiol-treated (OVX+E) groups,(More)
In type-2 diabetes, both insufficient insulin and excessive glucagon secretion contribute to hyperglycemia. We compared insulin, glucagon and somatostatin stores in pancreas obtained at autopsy of 20 lean and 19 obese non-diabetic (ND), and 18 type-2 diabetic (T2D) subjects. From concentrations and pancreas weight, total content of hormones was calculated.(More)
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