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Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins
The mitophagy receptor Nix interacts with LC3/GABARAP proteins, targeting mitochondria into autophagosomes for degradation. Here we present evidence for phosphorylation-driven regulation of theExpand
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Roles of ExoI and SbcCD nucleases in "reckless" DNA degradation in recA mutants of Escherichia coli.
Exponentially growing recA mutant cells of Escherichia coli display pronounced DNA degradation that starts at the sites of DNA damage and depends on RecBCD nuclease (ExoV) activity. As a consequenceExpand
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sbcB15 And DeltasbcB mutations activate two types of recf recombination pathways in Escherichia coli.
Escherichia coli cells with mutations in recBC genes are defective for the main RecBCD pathway of recombination and have severe reductions in conjugational and transductional recombination, as wellExpand
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Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy
In the last two decades, accumulating evidence pointed to the importance of autophagy in various human diseases. As an essential evolutionary catabolic process of cytoplasmatic component digestion,Expand
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Exonuclease VII is involved in "reckless" DNA degradation in UV-irradiated Escherichia coli.
The recA mutants of Escherichia coli exhibit an abnormal DNA degradation that starts at sites of double-strand DNA breaks (DSBs), and is mediated by RecBCD exonuclease (ExoV). This "reckless" DNAExpand
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Family-based analysis of vitamin D receptor gene polymorphisms and type 1 diabetes in the population of South Croatia
AbstractType 1 diabetes mellitus (T1DM) is a disease characterised by the autoimmune destruction of insulin-producing pancreatic β cells. Vitamin D is a known immune system modulator and its effectsExpand
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Could LogP be a principal determinant of biological activity in 18-crown-6 ethers? Synthesis of biologically active adamantane-substituted diaza-crowns.
18-crown-6 ethers are known to exert their biological activity by transporting K(+) ions across cell membranes. Using non-linear Support Vector Machines regression, we searched for structuralExpand
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RecF recombination pathway in Escherichia coli cells lacking RecQ, UvrD and HelD helicases.
In recBCD sbcB sbcC(D) mutants of Escherichia coli homologous recombination proceeds via RecF pathway, which is thought to require RecQ, UvrD and HelD helicases at its initial stage. It wasExpand
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Epigenetics and testicular germ cell tumors.
Abstract Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewingExpand
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RecQ helicase acts before RuvABC, RecG and XerC proteins during recombination in recBCD sbcBC mutants of Escherichia coli.
The RecQ helicase is required by the RecF recombination pathway that is operative in recBC(D) sbcB sbcC(D) mutants of Escherichia coli. Genetic data suggest that RecQ participates in resection of DNAExpand
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