Maira Ferreira de Noronha

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Fat accumulation within pancreatic acinar cells was observed by examination in patients consuming more than 30 gm./day of ethanol. Ultrastructural changes within the cell are described in these alcoholics without clinical pancreatitis, changes which are similar to those seen in the hepatocytes of alcoholics. The mechanisms which induce these ultrastructural(More)
Previous studies have shown that thyroid status affects the response of brown adipose tissue (BAT) to the sympathetic nervous system. For example, hypothyroidism is associated with the development of a marked synergism between alpha 1- and beta-adrenergic pathways to stimulate type II iodothyronine 5'-deiodinase activity. Hypothyroidism also attenuates the(More)
It has been important to extend database management systems to support new requirements of applications and administration. We focus in this paper on the automatic tuning feature, particularly manipulation of indexes. The architectural approach considered here is based on software agents. We briefly present the heuristics involved in the decision upon(More)
The histopathology of advanced chronic alcoholic pancreatitis is dominated by cellular degeneration, atrophy and fibrosis. Sequential changes in the histopathology of alcoholic pancreatic disease has been defined and traced from initial injury to end-stage disease. These sequential histopathologies have been correlated with clinical syndrome and secretory(More)
This article describes an intelligent system for financial planning and cashflow optimization named ICF: Intelligent Cash Flow. ICF is a computational tool for decision support which provides short-term and long-term financial managing strategies, considering financial products of the market. The ICF system makes use of Genetic Algorithms to elaborate cash(More)
The response of the pancreas to standard (1.0 U/kg) and augmented (4.0-5.0 U/kg) doses of secretin was compared in normal subjects and patients. The results of the investigation showed that for clinical purposes the standard test is sufficient for the diagnosis of pancreatic diseases causing gross destruction of the parenchyma. The augmented test is of(More)