Maiko Suzuki

MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers

Kaori Shima, Teppei Morikawa, +7 authors Shuji Ogino
Cancer Causes & Control
2010

O6-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme. MGMT promoter hypermethylation and epigenetic silencing often occur as early events in carcinogenesis. However, prognostic… (More)

Two separate regions essential for nuclear import of the hnRNP D nucleocytoplasmic shuttling sequence.

Maiko Suzuki, Megumi Iijima, Akira Nishimura, Yusuke Tomozoe, Daisuke Kamei, Michiyuki Yamada
The FEBS journal
2005

Heterogeneous nuclear ribonucleoprotein (hnRNP) D/AUF1 functions in mRNA genesis in the nucleus and modulates mRNA decay in the cytoplasm. Although it is primarily nuclear, it shuttles between the… (More)

Curculin exhibits sweet-tasting and taste-modifying activities through its distinct molecular surfaces.

Eiji Kurimoto, Maiko Suzuki, +8 authors Koichi Kato
The Journal of biological chemistry
2007

Curculin isolated from Curculigo latifolia, a plant grown in Malaysia, has an intriguing property of modifying sour taste into sweet taste. In addition to this taste-modifying activity, curculin… (More)

Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.

Tomohiro Nishioka, Maiko Suzuki, +5 authors Kyoko Imanaka-Yoshida
Journal of cardiovascular pharmacology
2007

Tenascin-C is an extracellular matrix glycoprotein that is supposed to be a profibrotic molecule in various fibrogenic processes. To elucidate its significance for myocardial fibrosis in the… (More)

Sirtuin1 and autophagy protect cells from fluoride-induced cell stress.

Maiko Suzuki, John Bartlett
Biochimica et biophysica acta
2014

Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase functioning in the regulation of metabolism, cell survival and organismal lifespan. Active SIRT1 regulates… (More)

Predictors of survival and causes of death in Japanese patients with systemic sclerosis.

Atsushi Hashimoto, Satoko Tejima, +6 authors Shunsei Hirohata
The Journal of rheumatology
2011

OBJECTIVE To clarify the mortality rates, causes of death, and contributing clinical factors in Japanese patients with systemic sclerosis (SSc). METHODS A cohort of 405 patients with SSc, who… (More)

Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells

Maiko Suzuki, Fumiaki Shinohara, M. Endo, Masaki Sugazaki, Seishi Echigo, Hidemi Rikiishi
Cancer Chemotherapy and Pharmacology
2008

During tumorigenesis, tumor suppressor and tumor-related genes are commonly silenced by aberrant DNA methylation in their promoter regions, which is one of the important determinants of… (More)

A Combination of Low-Intensity Pulsed Ultrasound and Nanohydroxyapatite Concordantly Enhances Osteogenesis of Adipose-Derived Stem Cells From Buccal Fat Pad.

Rika Nagasaki, Yoshiki Mukudai, +6 authors Tatsuo Shirota
Cell medicine
2015

The osteogenic induction of adipose-derived stem cells (ADSCs) has been regarded as an important step in bone tissue engineering. In the present study, we focused on the buccal fat pad (BFP) as a… (More)

Frameshift mutation in the PTCH2 gene can cause nevoid basal cell carcinoma syndrome

Katsunori Fujii, Hirofumi Ohashi, +4 authors Toshiyuki Miyashita
Familial Cancer
2013

Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by developmental defects and tumorigenesis. The gene responsible for NBCCS is PTCH1, encoding a receptor… (More)

Two cases of nevoid basal cell carcinoma syndrome associated with meningioma caused by a PTCH1 or SUFU germline mutation

Chihiro Kijima, Toshiyuki Miyashita, Maiko Suzuki, Hidehiro Oka, Kiyotaka Fujii
Familial Cancer
2012

Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by developmental defects and tumorigenesis. The gene responsible for NBCCS is PTCH1. The development of… (More)

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