Mahmoud S Abed

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OBJECTIVES The objective of this study was to examine the prevalence and trends of drug resistance of Mycobacterium tuberculosis at the Saudi Aramco Medical Services Organization. METHODS We retrospectively identified M tuberculosis isolates from January 1989 to December 2003. Antimicrobial susceptibility and clinical data were collected and analyzed. (More)
Clostridium difficile-associated diarrhea (CDAD) is an important healthcare-associated infection. However, there are no data from Saudi Arabia on this disease. A two-year prospective, observational study on the incidence of CDAD in a hospital in Saudi Arabia was carried out. Stool analysis for C. difficile toxins A and B was carried out by an enzyme-linked(More)
BACKGROUND Ventilator-associated pneumonia (VAP) increases in-hospital mortality of ventilated patients to 46%, compared with 32% for ventilated patients who do not develop VAP. In addition, VAP prolongs time spent on the ventilator, length of intensive care unit (ICU) stay, and length of hospital stay. METHODS In this study, we implemented VAP bundle to(More)
Retinoid acid receptors are DNA-binding proteins mediating the biological effects of ligands through transcriptional activation. It is known that the activity of the 26S proteasome is important for nuclear receptor-activated gene transcription. However, the molecular mechanism by which the 26S proteasome participates in this process is not well understood.(More)
BACKGROUND Hand hygiene is the single most important intervention to combat infections in any health care setting. However, adherence to hand hygiene practice remains low among health care workers. OBJECTIVES Our objective was to assess compliance with hand hygiene over time utilizing a multifaceted approach to hand hygiene. In addition, we assessed the(More)
OBJECTIVE The aim of the study was to evaluate the trends of antimicrobial resistance of Enterobacter spp. over time in a Saudi Arabian hospital. MATERIALS AND METHODS This is an in vitro surveillance study of the antibiotic susceptibility pattern among Enterobacter spp. recovered from outpatient and nosocomial isolates over a 7-year period from 2000 to(More)
BACKGROUND The compliance with influenza vaccination among health-care workers (HCWs) is known to be low. A multi-nationality survey to explore the reasons for such poor compliance has not been studied in depth. MATERIALS AND METHODS An epidemiologic survey to evaluate the compliance rates with influenza vaccination and possible associated reasons for(More)
OBJECTIVE To determine the trend of health care associated blood stream infection (HA-BSI) at Saudi Aramco Medical Services Organization. METHODS This prospective survey was conducted during the year 2002-2006. Definitions of HA-BSI infections were based on the Centers for Disease Control and Prevention categories. RESULTS There were a total of 1103(More)
BACKGROUND AND OBJECTIVE Peripherally inserted central venous catheters (PICCs) are alternatives to short-term central venous catheters and provide intravenous access in the acute hospital setting. In this study, we describe the rate of PICC-associated bloodstream infections (BSI). DESIGN AND SETTING Prospective cohort study using data on PICC lines(More)
BACKGROUND AND OBJECTIVES The World Health Organization (WHO) declared that pandemic influenza A (H1N1) was a public health emergency of international concern in April 2009. Herein, we describe the characteristics of patients in a Saudi Arabian hospital with and without H1N1 infection. METHODS We reviewed the records of patients admitted with(More)
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