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Khat (Catha edulis) extract increases oxidative stress parameters and impairs renal and hepatic functions in rats
Result: There was statistically significant increase in the activities of hepatic enzymes in treated rats compared to the control group. In addition, serum urea, bilirubin and phosphorousExpand
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Resveratrol Reverses Cadmium Chloride-induced Testicular Damage and Subfertility by Downregulating p53 and Bax and Upregulating Gonadotropins and Bcl-2 gene Expression
This study was performed to investigate the protective and therapeutic effects of resveratrol (RES) against CdCl2-induced toxicity in rat testes. Seven experimental groups of adult male rats wereExpand
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Coenzyme Q10 protects against acute consequences of experimental myocardial infarction in rats.
AIM Myocardial infarction (MI) due to sudden occlusion of a major coronary artery leads to a complex series of events that result in left ventricle (LV) impairment eventual heart failure. TherapeuticExpand
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In vivo, Acute, Normo-hypoglycemic, Antihyperglycemic, Insulinotropic Actions of Orally Administered Ethanol Extract of Citrullus colocynthis (L.) Schrab Pulp
Problem statement: Citrullus Colocynthis (L.) Schrab (cucurbitaceae family) (Handal) is a fruit commonly known as bitter apple or bitter cucu mber. Traditionally , Citrullus colocynthis has been usedExpand
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Derangement of hemopoiesis and hematological indices in Khat (Catha edulis) - treated rats
The purpose of this study was to identify the sub-acute toxic effects of Khat (Catha edulis) on hemopoiesis and hematological indices of white albino rats. Two groups, each of 10 rats, were used. InExpand
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Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling
The molecular mechanisms through which ghrelin exerts its cardioprotective effects during cardiac remodeling post-myocardial infarction (MI) are poorly understood. The aim of this study was toExpand
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QUERCETIN AMELIORATES DIABETIC NEPHROPATHY IN RATS VIA MODULATION OF RENAL NA + , K + -ATPASE EXPRESSION AND OXIDATIVE STRESS
Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoidExpand
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Concomitant down regulation of glycolytic enzymes, upregulation of gluconeogenic enzymes and potential hepato-nephro-protective effects following the chronic administration of the hypoglycemic,
Background Citrullus colocynthis pulp seedless extract has been demonstrated to have antihyperglycemic and insulinotropic effects. Problem statement: The mechanism(s) underlying the antihyperglycemicExpand
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Chronic exposure of rats to native high altitude increases in blood pressure via activation of the renin-angiotensin-aldosterone system.
OBJECTIVE To study the effect of chronic exposure to native high altitude (HA) on blood pressure, and to investigate the underlying mechanism of action. METHODS This study was carried out betweenExpand
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Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca2+-Activated K+ Channels
This study investigated the expression pattern, regulation of expression, and the role of hippocampal small-conductance Ca2+-activated K+ (SK) channels in memory deficits after cerebral hypoperfusionExpand
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