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Recreational drug use peaks in the developmental stage of adolescence, and exposure to drugs during adolescence may predict drug dependence in adulthood. Nevertheless, adolescent drug vulnerability is not widely studied in animal models of drug intake, and very few studies have investigated sex differences in drug-related behavior during adolescence. We(More)
Early developmental stress can have long-term physiological and behavioral effects on an animal. Developmental stress and early corticosterone (Cort) exposure affect song quality in many songbirds. Early housing condition can act as a stressor and affect the growth of nestlings and adult song, and improvements in housing condition can reverse adverse(More)
Stress has long lasting effects on physiology, development, behavior, reproductive success and the survival of an individual. These effects are mediated by glucocorticoids, such as corticosterone, via glucocorticoid receptors (GR), however the exact mechanisms underlying these effects are unknown. GR have been widely studied in mammals but little is known(More)
Steroid hormones and receptors play a role in regulating biological events underlying brain development and sexual differentiation. Current evidence indicates that circulating sex steroid hormones are not entirely responsible for development of neural sex differences in song birds such as the zebra finch. p68, as a coactivator specific for estrogen receptor(More)
Drug abuse peaks during adolescence, and exposure to drugs during adolescence predicts drug abuse in adulthood. Nevertheless, adolescence is not widely studied in animal models of drug intake. Moreover, few studies have investigated sex differences in drug-reinforced behavior during adolescence. We studied age-and sex-differences in acquisition and(More)
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