Mahendra Singh Ranawat

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As benzothiazole has proven to be good antimicrobial agent, a novel series of Schiff bases of benzothiazole derivatives were synthesized. Thus condensation of 5-[2-(1,3-benzothiazol-2-yl-amino) ethyl]-4-amino-3-mercapto-(4H)-1,2,4-triazole 5 with appropriate aromatic aldehydes afforded(More)
An asymmetric membrane capsule of cellulose acetate for osmotic delivery of flurbiprofen has been developed and influence of osmogents and solubilizing agent on in vitro drug release were evaluated. The capsule membrane was prepared by the phase inversion technique. To ensure the osmotic delivery of drug, two approaches were adopted: (i) the drug was(More)
The release of poorly water-soluble drug, flurbiprofen, through asymmetric membrane capsule of cellulose acetate containing different pore forming agents like glycerol, polyethylene glycol 400, and dibutyl phthalate, in presence of sodium lauryl sulfate was investigated. The asymmetric membrane was fabricated in the shape of capsule body and cap by phase(More)
Two simple, selective, rapid, precise and economical reverse phase high-pressure liquid chromatography methods have been developed; first method for estimation of nitazoxanide and second method for simultaneous estimation of nitazoxanide & ofloxacin from pharmaceutical dosage forms. The first method carried out on a Hypersil BDS C8 column (5μ particles(More)
A simple, selective, rapid, precise and isocratic reversed phase high-pressure liquid chromatography method has been developed and validated for estimation of related substances of Naproxen in pharmaceutical dosage form. It was performed on a YMC-ODS A Pack (5μ particles size) (250mm × 4.6mm) column using mobile phase containing Acetonitrile and 10 mM(More)
Microwave assisted organic synthesis (MAOS) has emerged as frontier in pharmaceutical research for synthesis of newer drugs. MAOS help not only in implementing GREEN chemistry but also led to the revolution in organic synthesis. For this purpose Methyl 2-acetoamidobenzoate was synthesized using methyl Anthranilate and acetic anhydride in presence of(More)
Objectives. The present study was aimed at investigating the wound healing effect of ethanolic extract of Cestrum nocturnum (L.) leaves (EECN) using excision and incision wound model. Methods. Wistar albino rats were divided into five groups each consisting of six animals; group I (left untreated) considered as control, group II (ointment base treated)(More)
A series of novel mannich bases of 2-substituted benzimidazoles was synthesized by the reaction of 2-substituted benzimidazoles with corresponding aldehyde and acetophenones. The structures of all synthesized compounds were confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR and LCMS. The compounds were evaluated for in vivo analgesic and in vivo(More)
Cefuroxime sodium is a semi-synthetic, broad-spectrum, cephalosporin antibiotic for parenteral administration. In the present paper a high-performance liquid chromatographic and an UV spectrophotometric method were developed and validated for the quantitative determination. The different analytical parameters such as linearity, precision, accuracy,(More)
A. latifolia grown in the Borimalan forest block in Prasad range (24°11′N and 73°42′ E) exerts clear positive correlations between CBH (circumference breast height)and number of growth rings of bole and branches, tree height, total biomass and leaf area. The net above-ground biomass is 3.95 × 104 kg ha-1. The average increment in non-photosynthetic (trunk +(More)