• Publications
  • Influence
Simultaneous dimension reduction and adjustment for confounding variation
  • Z. Lin, Can Yang, +10 authors W. Wong
  • Computer Science, Medicine
  • Proceedings of the National Academy of Sciences
  • 7 December 2016
TLDR
We extend principal component analysis (PCA) to propose AC-PCA for simultaneous dimension reduction and adjustment for confounding (AC) variation. Expand
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Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations
TLDR
Coupled clustering is a problem not covered by existing clustering methods. Expand
  • 52
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Unsupervised clustering and epigenetic classification of single cells
Characterizing epigenetic heterogeneity at the cellular level is a critical problem in the modern genomics era. Assays such as single cell ATAC-seq (scATAC-seq) offer an opportunity to interrogateExpand
  • 51
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Model-Based Approach to the Joint Analysis of Single-Cell Data on Chromatin Accessibility and Gene Expression
TLDR
We develop a model-based clustering method for the integrative analysis of single-cell chromatin accessibility and gene expression data. Expand
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A new method for variable elimination in systems of inequations
TLDR
In this paper, we present a new method for variable elimination in systems of inequalities which is much faster than the Fourier-Motzkin Elimination (FME) method. Expand
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Predicting transcription factor binding motifs from DNA-binding domains, chromatin accessibility and gene expression data
Abstract Transcription factors (TFs) play crucial roles in regulating gene expression through interactions with specific DNA sequences. Recently, the sequence motif of almost 400 human TFs have beenExpand
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Kinematic analysis of the gait of adult sheep during treadmill locomotion: Parameter values, allowable total error, and potential for use in evaluating spinal cord injury
We are developing a novel intradural spinal cord (SC) stimulator designed to improve the treatment of intractable pain and the sequelae of SC injury. In-vivo ovine models of neuropathic pain andExpand
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Degrees of Freedom Region of Wireless X Networks Based on Real Interference Alignment
TLDR
We first consider a single hop wireless X network with K transmitters and J receivers. Expand
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Multiple access channel with correlated channel states and cooperating encoders
TLDR
In this paper, a two-user discrete memoryless multiple-access channel (DM-MAC) with correlated channel states, each known at one of the encoders is considered, in which each encoder transmits independent messages and tries to cooperate with the other one. Expand
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Multiple-access channel with correlated states and cooperating encoders
TLDR
A two-user discrete memoryless multiple-access channel with two correlated states known non-causally at the corresponding encoder is considered. Expand
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