Mahdi Saheb Jam Atabaki

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UNLABELLED Single nucleotide polymorphisms in pre‑microRNA (miRNA) may alter miRNA expression levels or processing and contribute to susceptibility in a wide range of diseases. The present study aimed to evaluate the possible association between rs2910164 and rs3746444 of the pre-miRNA (hsa-mir-146a and hsa-mir-499) polymorphisms and susceptibility to(More)
BACKGROUND Rheumatoid arthritis (RA) is a chronic inflammatory disease with many genetic factors predisposing to disease susceptibility. The aim of the present study was to investigate the impact of CD226 rs727088 and rs763361 polymorphisms and susceptibility to RA in a sample of the Iranian population. METHODS This case-control study was carried out on(More)
Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. IRGM1 is an important protein in the innate immune response against intracellular pathogens by regulating autophagy. Polymorphisms in the IRGM genes are known to influence expression levels and may be associated with outcome of infections. This case-control study was done on 150(More)
In this study we aimed to evaluate the possible association of PTPN22 rs2476601 as well as epidermal growth factor receptor (EGFR) rs17337023 gene polymorphism and rheumatoid arthritis (RA) in a sample of Iranian population. This case-control study was performed on 120 patients with RA and 120 healthy subjects. Genomic DNA was extracted from whole blood and(More)
BACKGROUND/AIMS A variety of techniques are employed for planing and scaling of the superficial root surfaces, of which hand and ultrasonic instrumentations have been preferentially used in routine periodontics clinics. This study was undertaken to compare the effectiveness of ultrasonic scalers and hand curettes in facilitating fibroblast attachment to the(More)
  • Güneydoğu İran Zahedan’da, Muhtemel İlişki, +6 authors Mohsen Taheri
  • 2012
Hastalar ve yöntemler: Bu olgu kontrollü çalışmaya İranlı 100 RA hastası (88 kadın, 12 erkek; ort. yaş 44.1±13.2 yıl; dağılım 17-75 yıl) ve 100 sağlıklı birey (68 kadın ve 32 erkek, ort. yaş 45.7±9.6 yıl; dağılım 23-70 yıl) dahil edildi. GSTP1 polimorfizm tetra amplifikasyona dirençli mutasyon sistem polimeraz zincir reaksiyonu (Tetra-ARMS-PCR) ile(More)
Single nucleotide polymorphisms in pre-microRNA (miRNA) may alter miRNA expression levels or processing and contribute to susceptibility in a wide range of diseases. The present study aimed to evaluate the possible association between rs2910164 and rs3746444 of the pre-miRNA (hsamir-146a and hsa-mir-499) polymorphisms and susceptibility to rheumatoid(More)
Rheumatoid arthritis (RA) is a complex genetic disease. The lectin, galactoside-binding, soluble, 3 (LGALS3) gene, encodes a member of the galectin family of carbohydrate binding proteins, and is one of the best examples of a non-human leukocyte antigen gene associated with a risk for RA in various populations. In the current study, the association between(More)
Rheumatoid arthritis (RA) is a systemic autoimmune disease predominantly involving the synovial joints and affects up to 1% of adults worldwide. The aim of the present study was to determine whether the interleukin-1 receptor (IL1R)-associated kinase (IRAK1) rs3027898 gene polymorphism confers susceptibility to RA in a sample of patients from Iran. This(More)
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