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Chitosan was prepared from shrimp processing waste (shell) using the same chemical process as described for the other crustacean species with minor modification in the treatment condition. The physicochemical properties, molecular weight (165394g/mole), degree of deacetylation (75%), ash content as well as yield (15%) of prepared chitosan indicated that(More)
The objectives of this study were to describe the global profile of biomedical research productivity and to examine any improvement seen in it in the developing world during the period 1990-2000. Biomedical research articles published during 1990-2000 were accessed through the Medline database. The number of (journal) articles originating from each of the(More)
OBJECTIVE The objective of this study was to elicit the factors related to worldwide variation in biomedical research productivity. METHODS Biomedical research articles published in 1990-2000 were accessed through the MEDLINE database. The number of articles (journal articles) originating from each of the countries of the world was elicited and normalized(More)
Taken orally, the drug dimethyl fumarate (DMF) has been shown to improve functional outcomes for patients with MS; however, it is unclear how DMF mediates a protective effect. DMF and, more so, its active metabolite, monomethyl fumarate, are known agonists of the hydroxycarboxylic acid receptor 2 (HCA₂), a G protein-coupled membrane receptor. Here, we(More)
OBJECTIVE To investigate the degree of Japan's contribution in basic and clinical research in the last decade. METHODS Original articles published in 1990-2000 in highly reputed basic and clinical journals were accessed through MEDLINE database. The number of articles having affiliation with a Japanese institution was counted separately for basic and(More)
Drug abuse is an alarming problem in Bangladesh where there are 1.7 million drug abusers (1). The number is increasing greatly over recent years. Among drug abusers, intravenous drug use has the potential to turn a slow HIV epidemic into an explosive and devastating one, as was observed in Thailand and northern India (2,3). Drug use shortens life(More)
OBJECTIVE To estimate the effects of using depot medroxyprogesterone acetate (DMPA) or oral contraceptives (OCs) containing 20 micrograms ethinyl estradiol and 0.15 mg desogestrel on serum lipid levels. METHODS Serum lipids were measured at baseline and every 6 months thereafter for 3 years in 703 white, African-American, and Hispanic women using DMPA,(More)
OBJECTIVE The purpose of this study was to summarize the available evidence on timing of perioperative antibiotics for cesarean delivery. STUDY DESIGN We searched the literature for studies that compare prophylactic antibiotics for cesarean delivery that are given before the procedure vs at cord clamping. Only randomized controlled trials were included.(More)
The ketone body β-hydroxybutyrate (BHB) is an endogenous factor protecting against stroke and neurodegenerative diseases, but its mode of action is unclear. Here we show in a stroke model that the hydroxy-carboxylic acid receptor 2 (HCA2, GPR109A) is required for the neuroprotective effect of BHB and a ketogenic diet, as this effect is lost in Hca2(-/-)(More)
The Binax NOW Flu A and Flu B (Binax NOW), direct fluorescent assay (DFA), and viral culture were evaluated and compared with a composite of viral culture or reverse transcription polymerase chain reaction (RT-PCR). Participants with medically attended acute respiratory illness were identified through active surveillance during the 2006 to 2007 season, and(More)